Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about METABOLIC SYNDROME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
METABOLIC_SYNDROME["METABOLIC SYNDROME"]
METABOLIC_SYNDROME -->|"activates"| Lipid_Metabolism["Lipid Metabolism"]
METABOLIC_SYNDROME -->|"activates"| Mtor["Mtor"]
METABOLIC_SYNDROME -->|"activates"| Lysosomal_Degradation["Lysosomal Degradation"]
METABOLIC_SYNDROME -->|"activates"| Autophagy["Autophagy"]
METABOLIC_SYNDROME -->|"target for"| Epigenetic["Epigenetic"]
METABOLIC_SYNDROME -->|"target for"| Tgf__["Tgf-Beta"]
METABOLIC_SYNDROME -->|"target for"| Insulin_Signaling["Insulin Signaling"]
METABOLIC_SYNDROME -->|"target for"| Ferroptosis["Ferroptosis"]
METABOLIC_SYNDROME -->|"regulates"| Immune_Response["Immune Response"]
ACTB["ACTB"] -->|"activates"| METABOLIC_SYNDROME
PPARA["PPARA"] -->|"activates"| METABOLIC_SYNDROME
CAT["CAT"] -->|"activates"| METABOLIC_SYNDROME
SQSTM1["SQSTM1"] -->|"activates"| METABOLIC_SYNDROME
RPS6KB1["RPS6KB1"] -->|"activates"| METABOLIC_SYNDROME
RAB7A["RAB7A"] -->|"activates"| METABOLIC_SYNDROME
SREBF1["SREBF1"] -->|"activates"| METABOLIC_SYNDROME
EIF4EBP1["EIF4EBP1"] -->|"activates"| METABOLIC_SYNDROME
CTSD["CTSD"] -->|"activates"| METABOLIC_SYNDROME
PPARGC1A["PPARGC1A"] -->|"activates"| METABOLIC_SYNDROME| Source | Relation | Type | Str |
|---|---|---|---|
| CIRCADIAN DISRUPTION | associated_with | entity | 0.90 |
| HYPOTHALAMUS | protects_against | brain_region | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||